Receptive fields
نویسنده
چکیده
Drosophila APC has a role in maintaining adherens junctions, and also helps to tether mitotic spindles to the cortex and to orient them in the epithelial plane. In mammalian cells, APC has been implicated in cell migration. APC also helps safeguard the fidelity of chromosome segregation in mitotic cells. Loss of APC’s various functions at the cell periphery may contribute to tumour progression. The multitude of these functions could explain why APC is such a potent tumour suppressor.
منابع مشابه
Effect of phasic electrical locus coeruleus stimulation on inhibitory and excitatory receptive fields of layer V barrel cortex neurons in male rat
Introduction: It is believed that Locus Coeruleus (LC) influences the sensory information processing. However, its role in cortical surround inhibitory mechanism is not understood. In this experiment, using controlled mechanical displacement of whiskers we investigated the effect of phasic electrical stimulation of LC on response of layer V barrel cortical neurons in anesthetized rat. Methods: ...
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ورودعنوان ژورنال:
- Current Biology
دوره 13 شماره
صفحات -
تاریخ انتشار 2003